Which medications in the drug class Immunosuppressive agents are used in the treatment of Antiphospholipid Syndrome?

Updated: Nov 24, 2020
  • Author: Suneel Movva, MD; Chief Editor: Herbert S Diamond, MD  more...
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Immunosuppressive agents

Consider immunosuppressive agents in select cases (eg, refractory APS, CAPS).

Cyclophosphamide (Cytoxan, Neosar)

Chemically related to nitrogen mustards. As an alkylating agent, mechanism of action of active metabolites may involve cross-linking of DNA, which may interfere with growth of normal and neoplastic cells. Has not been shown to be effective in APS.

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