Which medications are used in the treatment of antiphospholipid syndrome (APS)?

Updated: Nov 24, 2020
  • Author: Suneel Movva, MD; Chief Editor: Herbert S Diamond, MD  more...
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The suggested medications include heparin, warfarin, aspirin, and, in selected cases, hydroxychloroquine, intravenous immunoglobulin, and corticosteroids.

Corticosteroids are rarely used for the treatment of recurrent fetal loss because of the increased risk of maternal morbidity. Generally, the use of corticosteroids is reserved for specific nonthrombotic manifestations, such as associated thrombocytopenia, autoimmune hemolytic anemia, or the treatment of an underlying connective-tissue disease.

Prescribe antihypertensive drugs when necessary.

Administer antihyperlipidemic agents including statins when appropriate.

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