Which antibody testing may be useful in the diagnosis of antiphospholipid syndrome (APS)?

Updated: Sep 30, 2018
  • Author: Suneel Movva, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Additional antibodies directed against phospholipid/phospholipid-protein complexes for which testing may be useful in selected cases (seronegative APS, because they are not part of the 2006 consensus criteria) include the following [17, 18, 8] :

  • IgA aCL
  • IgA beta-2 glycoprotein I
  • Anti-phosphatidylserine antibodies
  • Anti-phosphatidylethanolamine antibodies
  • Anti-prothrombin antibodies
  • Antibodies against the phosphatidylserine-prothrombin complex

For further information, see Antiphospholipid Antibodies.


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