Which patient groups have the highest prevalence of acute rheumatic fever (ARF)?

Updated: Dec 10, 2020
  • Author: Robert J Meador, Jr, MD; Chief Editor: Herbert S Diamond, MD  more...
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No general clear-cut sex predilection for ARF has been reported, but certain of its manifestations seem to be sex variable. For example, chorea and tight mitral stenosis occur predominantly in females, while aortic stenosis develops more often in males.

The initial attack of ARF occurs most frequently in persons aged 5-15 years and rarely occurs in persons older than 30 years. [20] The disease may cluster in families. In some countries, a shift into older groups may be a trend.

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