Which medications in the drug class Immunosuppressants are used in the treatment of Ankylosing Spondylitis and Undifferentiated Spondyloarthropathy?

Updated: Sep 03, 2019
  • Author: Lawrence H Brent, MD; Chief Editor: Herbert S Diamond, MD  more...
  • Print
Answer

Immunosuppressants

Immunosuppressants inhibit key factors in the immune system that are responsible for inflammatory responses.

Methotrexate (Trexall, Otrexup, Rasuvo)

Methotrexate has an unknown mechanism of action in AS; it may affect immune function. Effects are observed in the 3-6 weeks following administration. Methotrexate ameliorates symptoms (eg, pain, swelling, stiffness), but there is no evidence that it induces remission. Adjust the dose gradually to obtain a satisfactory response.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!