What are the American College of Rheumatology treatment guidelines for active ankylosing spondylitis (AS) despite treatment with NSAIDs?

Updated: Jul 17, 2018
  • Author: Lawrence H Brent, MD; Chief Editor: Herbert S Diamond, MD  more...
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Conditionally recommend against treatment with slow-acting antirheumatic drugs (SAARDs)

Strongly recommend treatment with a tumor necrosis factor inhibitor (TNFi) over no treatment with TNFi

No recommendation for any particular TNFi as the preferred choice

In adults with active AS despite treatment with NSAIDs and who have contraindications to TNFi, conditionally recommend treatment with a SAARD over treatment with a non-TNFi biologic agent

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