What are the features of axial spondyloarthropathy (SpA)?

Updated: Feb 02, 2021
  • Author: Lawrence H Brent, MD; Chief Editor: Herbert S Diamond, MD  more...
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SpA features are as follows:

  • Inflammatory back pain

  • Arthritis

  • Enthesitis (head)

  • Uveitis

  • Dactylitis

  • Psoriasis

  • Crohn disease

  • Good response to NSAIDs

  • Family history of SpA

  • HLA-B27

  • Elevated C-reactive protein level

However, the use of this classification in clinical practice does pose the risk of misdiagnosis, especially in a population with a low pretest probability of disease. This could lead to inappropriate use of tumor necrosis factor (TNF) inhibitors in patients who actually have chronic mechanical back pain. [87]

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