Which genes have been excluded in the etiology of ankylosing spondylitis (AS)?

Updated: Jul 17, 2018
  • Author: Lawrence H Brent, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Numerous genes have been excluded in the etiology of ankylosing spondylitis, such as the following [29] :

  • TGF-β
  • MMP3
  • IL-10
  • IL-6
  • Immunoglobulin (Ig) allotypes
  • TCR
  • TLR4
  • NOD2/CARD15
  • CD14
  • NFbBIL1
  • PTPN22

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