What are the recommendations of an international task force on treating axial and peripheral spondyloarthritis?

Updated: Feb 02, 2021
  • Author: Lawrence H Brent, MD; Chief Editor: Herbert S Diamond, MD  more...
  • Print

Guidelines issued by an international task force on treating axial and peripheral spondyloarthritis to target include the following recommendations [136] :

  • The treatment target should be clinical remission/inactive disease of musculoskeletal (arthritis, dactylitis, enthesitis, axial disease) and extra-articular manifestations.
  • The treatment target should be individualized on the basis of current clinical manifestations, and the treatment modality should be considered when defining the time required to reach the target.
  • Clinical remission/inactive disease is defined as the absence of clinical and laboratory evidence of significant disease activity; low or minimal disease activity may be an alternative treatment target .
  • Disease activity should be measured on the basis of clinical signs and symptoms, and acute phase reactants.
  • Validated measures of musculoskeletal disease activity and assessment of cutaneous and/or other relevant extra-articular manifestations should be used in clinical practice to define the target and to guide treatment decisions; the frequency of the measurements depends on the level of disease activity.
  • In axial spondyloarthritis, the Ankylosing Spondylitis Disease Activity Score (ASDAS) is a preferred measure.
  • The choice of the target and of the disease activity measure should take comorbidities, patient factors, and drug-related risks into account.
  • In addition to clinical and laboratory measures, imaging results may be considered in clinical management.
  • Once the target is achieved, it should ideally be maintained throughout the course of the disease. 
  • The patient should be appropriately informed and involved in the discussions about the treatment target and the risks and benefits of the strategy planned to reach this target.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!