What are the American College of Rheumatology treatment guidelines for AS-related comorbidities?

Updated: Feb 02, 2021
  • Author: Lawrence H Brent, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

In adults with AS-related comorbidities:

  • In patients with acute iritis, strongly recommend treatment by an ophthalmologist to decrease the severity, duration, or complications of episodes
  • In patients with recurrent iritis, conditionally recommend prescription of topical glucocorticoids over no prescription for prompt at-home use in the event of eye symptoms, to decrease the severity or duration of iritis episodes
  • In patients with recurrent iritis,conditionally recommend treatment with TNFi monoclonal antibodies over treatment with other biologics
  • In patients with inflammatory bowel disease, do not recommend any particular NSAID as the preferred choice to decrease the risk of worsening of inflammatory bowel disease symptoms
  • In patients with inflammatory bowel disease, conditionally recommend treatment with TNFi monoclonal antibodies over treatment with other biologics

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