What is the methotrexate regimen for the remission maintenance of granulomatosis with polyangiitis (GPA)?

Updated: Oct 09, 2019
  • Author: Christopher L Tracy, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

20-25 mg weekly, oral or subcutaneous

Must have normal renal function (ie, Cr < 1.5mg/dL)

Required laboratory monitoring - CBC, Cr, LFTs


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