Which clinical history findings are characteristic of pulmonary involvement in granulomatosis with polyangiitis (GPA)?

Updated: Oct 09, 2019
  • Author: Christopher L Tracy, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Pulmonary involvement can be asymptomatic, insidious in onset, or severe and fulminant. Pulmonary disease may cause any of the following [1] :

  • Pulmonary infiltrates (71% of patients)

  • Cough (34%)

  • Hemoptysis (18%)

  • Chest discomfort (8%)

  • Dyspnea (7%)

  • Diffuse alveolar hemorrhage (DAH) due to alveolar capillaritis (5%-45% [2] )


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