What are the specificity and sensitivity of temporal artery biopsy (TAB) in the diagnosis of giant cell arteritis (GCA) (temporal arteritis)?

Updated: Sep 03, 2020
  • Author: Mythili Seetharaman, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

A positive TAB is diagnostic of GCA (100% specificity). The reported sensitivity of TAB has ranged widely, from as low as 15% to as high as 87%. [112] The histopathological changes on TAB often correlate with clinical features of severity. [12]


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