How is disease activity assessed in Takayasu arteritis?

Updated: Nov 14, 2018
  • Author: Jefferson R Roberts, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Assessing disease activity in patients with Takayasu arteritis is frequently challenging, since clinical, biologic, and radiologic information do not always correlate. Prospective study criteria established by Kerr et al (National Institutes of Health) are used to assess disease activity in patients with Takayasu arteritis. New onset or worsening of 2 or more of the following features indicates active disease [16] :

  • Systemic features, such as fever and arthralgias (no identified cause)

  • Elevated erythrocyte sedimentation rate

  • Features of vascular ischemia or inflammation, such as claudication, diminished or absent pulse, bruit, carotodynia, or asymmetrical blood pressure in either the upper or lower limbs (or both)

  • Typical angiographic features


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