What are the American College of Rheumatology (ACR; 1990) diagnostic criteria for Takayasu arteritis?

Updated: Nov 14, 2018
  • Author: Jefferson R Roberts, MD; Chief Editor: Herbert S Diamond, MD  more...
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The American College of Rheumatology (ACR; 1990) put forward the following diagnostic criteria:

  • Angiographic criteria must show narrowing or occlusion of the entire aorta, its primary branches, or large arteries in the proximal upper or lower extremities

  • These changes are not due to arteriosclerosis, fibromuscular dysplasia, or similar causes

  • Changes are usually focal or segmental

These criteria probably allow greater flexibility to account for variability in actual clinical practice. In comparison to the Ishikawa criteria, which were established based on Japanese patients only, the ACR criteria may better reflect the North American population. The lesions can include stenosis, occlusion, or aneurysms.

The sensitivity and specificity of the American College of Rheumatology criteria are 90.5% and 97.9%, respectively.

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