What are conditions to consider in the differential diagnoses of Takayasu arteritis?

Updated: Nov 14, 2018
  • Author: Jefferson R Roberts, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Takayasu arteritis is rare and difficult to diagnose. Initially, symptoms are vague; the disease may progress considerably until an angiogram is performed. Conditions to consider in the differential diagnosis of Takayasu arteritis include the following:

  • Cerebral aneurysms

  • IgG4-related disease [29]

  • Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)
  • Intracranial hemorrhage

  • Lacunar syndromes

  • Neurofibromatosis type 1

  • Neurofibromatosis type 2

  • Polyarteritis nodosa

  • Sarcoidosis and neuropathy

  • Subarachnoid hemorrhage

  • Syncope and related paroxysmal spells

  • Fibromuscular dysplasia

  • Spondyloarthropathies

  • Thromboembolism

  • Traumatic stenosis

  • Radiation fibrosis

  • Ergotism

  • Ehlers-Danlos syndrome

  • Marfan syndrome

  • Neurofibromatosis

  • Syphilis

  • Cogan syndrome

  • Dilated cardiomyopathy

  • Erythema nodosum

  • Relapsing polychondritis

  • Amaurosis fugax

  • Ocular pathology

  • Other arteritides

  • Other large vessel diseases (eg, neurofibromatosis of the abdominal aorta)

  • Carotid disease and stroke

  • Reversible posterior leukoencephalopathy syndrome

  • Common variable immunodeficiency syndrome

  • Keratouveitis

  • Posterior scleritis

  • Polymyalgia rheumatica

  • Subclavian steal syndrome

  • Raynaud phenomenon


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