How is systemic lupus erythematosus (SLE) disease activity measured?

Updated: Aug 04, 2021
  • Author: Christie M Bartels, MD, MS; Chief Editor: Herbert S Diamond, MD  more...
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Answer

It is important to distinguish between the disease activity and the damage index (irreversible organ dysfunction). Although the most effective instrument to measure SLE disease activity is still open to debate, there are several validated measures, including the Systemic Lupus Activity Measure (SLAM), SLEDAI, Lupus Activity Index (LAI), European Consensus Lupus Activity Measurement (ECLAM), and British Isles Lupus Activity Group (BILAG) Index.


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