Which medications are used in the treatment of systemic lupus erythematosus (SLE)?

Updated: Aug 04, 2021
  • Author: Christie M Bartels, MD, MS; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Medications used to treat SLE manifestations include the following:

  • Antimalarials (eg, hydroxychloroquine)

  • Corticosteroids (eg, methylprednisolone, prednisone), short-term use recommended

  • Nonbiologic DMARDS: Cyclophosphamide, methotrexate, azathioprine, mycophenolate, cyclosporine 

  • Nonsteroidal anti-inflammatory drugs (NSAIDS; eg, ibuprofen, naproxen, diclofenac)

  • Biologic DMARDs (disease-modifying antirheumatic drugs): Belimumab, rituximab, and/or IV immune globulin

See Treatment and Medication for more detail.


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