Which medications in the drug class Pulmonary, Tyrosine Kinase Inhibitors are used in the treatment of Scleroderma?

Updated: Sep 09, 2019
  • Author: Sergio A Jimenez, MD, MACR, FACP, FRCP(UK Hon); Chief Editor: Herbert S Diamond, MD  more...
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Answer

Pulmonary, Tyrosine Kinase Inhibitors

Nintedanib is a tyrosine kinase inhibitor that targets growth factors (eg, vascular endothelial growth factor receptor [VEGFR], fibroblast growth factor receptor [FGFR], platelet-derived growth factor receptor [PDGFR] 1-3, colony-stimulating factor 1 receptor [CSFIR]) that are implicated in the pathogenesis of interstitial lung diseases.

Nintedanib (Ofev)

Indicated to slow the rate of decline in pulmonary function in patients who have interstitial lung disease associated with scleroderma.


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