What are pulmonary function test (PFT) criteria for pulmonary involvement in scleroderma?

Updated: Sep 09, 2019
  • Author: Sergio A Jimenez, MD, MACR, FACP, FRCP(UK Hon); Chief Editor: Herbert S Diamond, MD  more...
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These authors recommended the following as PFT criteria for pulmonary involvement [159] :

  • Forced vital capacity (FVC) or hemoglobin‐adjusted diffusing capacity of the lungs for carbon monoxide (DLCO) between 80% and 45% predicted
  • A decline in FVC of >10% or DLCO of >15% on serial testing
  • Failure to respond to initial therapy on serial PFT monitoring

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