What are the GI signs and symptoms of scleroderma?

Updated: Sep 09, 2019
  • Author: Sergio A Jimenez, MD, MACR, FACP, FRCP(UK Hon); Chief Editor: Herbert S Diamond, MD  more...
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GI findings in systemic sclerosis include the following:

  • Gastroesophageal reflux caused by lower esophageal sphincter (LES) incompetence and decreased or absent peristalsis in the lower two thirds of the esophagus (may lead to hoarseness, dysphagia and aspiration pneumonia)

  • Dyspepsia, bloating, and early satiety

  • Intestinal pseudo-obstruction

  • Constipation alternating with diarrhea from bacterial overgrowth (may lead to malabsorption)

  • Fecal incontinence

  • Malnutrition from inadequate caloric intake

  • Chronic iron deficiency anemia from occult blood loss

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