What are the dermatologic signs and symptoms of scleroderma?

Updated: Nov 13, 2018
  • Author: Sergio A Jimenez, MD, MACR, FACP, FRCP(UK Hon); Chief Editor: Herbert S Diamond, MD  more...
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Answer

Skin manifestations of systemic sclerosis are as follows:

  • Progressive skin tightness and induration, often preceded by swelling and puffiness (edematous stage) that does not respond to diuretic therapy

  • Skin induration initially affects the fingers (sclerodactyly) and extends proximally (see image below).

    Tightening of the skin in the face, with a charact Tightening of the skin in the face, with a characteristic beaklike facies and paucity of wrinkles.
  • Tightening of the skin in the face is often noted very early in the course of the disease (see image below)

    Sclerodactyly with digital ulceration, loss of ski Sclerodactyly with digital ulceration, loss of skin creases, joint contractures, and sparse hair.
  • Prominent skin pigmentary changes both hyperpigmentation and hypopigmentation (see image below)

    Anterior chest demonstrating salt-and-pepper hypop Anterior chest demonstrating salt-and-pepper hypopigmentation and diffuse hyperpigmentation in a white woman.
  • Diffuse pruritus


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