What are the possible complications of scleroderma?

Updated: Jun 24, 2020
  • Author: Sergio A Jimenez, MD, MACR, FACP, FRCP(UK Hon); Chief Editor: Herbert S Diamond, MD  more...
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Complications of systemic sclerosis include the following:

  • Digital infarctions

  • Pulmonary hypertension

  • Myositis

  • Renal failure

Frerix and colleagues have proposed that osteonecrosis of the lunate bone (Kienböck disease), while very rare in the general population, may be a frequent manifestation of systemic sclerosis, and may be linked to vasculopathy from the disorder. [31] Lunate osteonecrosis manifests as pain and stiffness in the affected wrist and decreased grip strength in the hand.

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