What are the racial predilections of scleroderma?

Updated: Nov 13, 2018
  • Author: Sergio A Jimenez, MD, MACR, FACP, FRCP(UK Hon); Chief Editor: Herbert S Diamond, MD  more...
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Answer

Systemic sclerosis affects individuals of all races. [26, 27, 28, 29] However, incidence rates, severity and mortality may vary among ethnic groups.

Recent studies have documented a higher general and age-specific incidence rate in blacks than in whites. It has also been shown that affected African Americans develop more severe disease and have poorer outcomes when compared with other ethnic groups. [26, 27, 28, 29]

The highest prevalence of systemic sclerosis in the US is among the Oklahoma Choctaw Indians. The prevalence in the Choctaws is 469 cases per 100,000 population, which is higher than in non-full blood Choctaw (31 per 100,000) and 20 times higher than the national average. [30]


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