How is chronic Lyme disease differentiated from rheumatoid arthritis (RA)?

Updated: Feb 07, 2020
  • Author: Howard R Smith, MD; Chief Editor: Herbert S Diamond, MD  more...
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Chronic Lyme disease typically involves only 1 joint, most commonly the knee, and is associated with positive serologic tests. Human parvovirus B19 infection in adults can occasionally mimic RA.

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