How is gouty arthritis differentiated from rheumatoid arthritis (RA)?

Updated: Aug 22, 2019
  • Author: Howard R Smith, MD; Chief Editor: Herbert S Diamond, MD  more...
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During the early years of disease, gouty arthritis is almost always intermittent and monoarticular; in later years, it can become a chronic polyarticular process that mimics RA. Gouty tophi can at times resemble rheumatoid nodules. The early history of intermittent monoarthritis and the presence of synovial urate crystals are distinctive features of gout.

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