What are the possible complications of reactive arthritis (ReA)?

Updated: Dec 24, 2020
  • Author: Carlos J Lozada, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Complications of ReA include the following:

  • Recurrent arthritis (15-50%)

  • Chronic arthritis or sacroiliitis (15-30%)

  • Ankylosing spondylitis (30-50% of HLA-B27–positive patients)

  • Urethral stricture

  • Aortic root necrosis

  • Secondary glaucoma

  • Cataracts

  • Cystoid macular edema

  • Posterior and anterior synechiae

  • Cyclitic membrane

  • Vitreous opacification

  • Ankylosing spondylitis, psoriatic arthritis, and sacroiliitis

  • Erythroderma (rare)

In severe cases, functional impairment may be severe, and a chronic and prolonged clinical course is followed by sequelae (eg, urethral stenosis, chronic arthritis, or ocular impairment).


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