How is reactive arthritis (ReA) treated?

Updated: Dec 24, 2020
  • Author: Carlos J Lozada, MD; Chief Editor: Herbert S Diamond, MD  more...
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Pharmacologic agents that may be used in treating ReA include the following:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) - These are the mainstays of therapy
  • Corticosteroids (topical, intra-articular, and systemic)

  • Antibiotics (for Chlamydia-related ReA in particular) - Tetracyclines are commonly given

  • Disease-modifying antirheumatic drugs (DMARDs) - Typically given when NSAIDs are ineffective or contraindicated, these include sulfasalazine, methotrexate, and anti−tumor necrosis factor (TNF) medications such as etanercept and infliximab

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