What are the cutaneous symptoms of polyarteritis nodosa (PAN)?

Updated: Nov 14, 2017
  • Author: Dana Jacobs-Kosmin, MD, FACP; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Cutaneous symptoms in PAN include the following [6] (see the images below):

  • Livedo reticularis that does not blanch with active pressure

  • Ulcerations - Especially on the lower extremities, near the malleoli and on the calf

  • Digital ischemia - May be accompanied by splinter hemorrhages and, sometimes, gangrene

  • Nodules - Usually on the lower extremities (like ulcers); nodules are the least common skin manifestation of PAN

Tender, hyperpigmented, firm subcutaneous nodules Tender, hyperpigmented, firm subcutaneous nodules with a background of livedo reticularis common in cutaneous polyarteritis nodosa (PAN).
Tender erythematous nodules with central "punched Tender erythematous nodules with central "punched out" ulcerations common in cutaneous polyarteritis nodosa (PAN).
Livedo reticularis in polyarteritis nodosa (PAN). Livedo reticularis in polyarteritis nodosa (PAN).

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