What are the uncommon symptoms of polyarteritis nodosa (PAN)?

Updated: Dec 17, 2020
  • Author: Dana Jacobs-Kosmin, MD, FACP; Chief Editor: Herbert S Diamond, MD  more...
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Less common symptoms reported in PAN include the following:

  • Genitourinary - Patients may develop pain over the testicular or ovarian area. In rare cases, testicular infarction may occur; testicular pain is usually unilateral [44]

  • Cardiac - Chest pain, dyspnea, palpitations, pericarditis, myocardial infarction, and congestive heart failure; cardiac disease affects 35% of patients with PAN, but most affected patients are asymptomatic

  • Ophthalmologic - Blurred vision

  • Neuropsychiatric - Headache, psychosis, [45] and depression

  • Muscular - Rarely, PAN may present as only skeletal muscle pain and fever [46]

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