What are the complications of polyarteritis nodosa (PAN)?

Updated: Nov 14, 2017
  • Author: Dana Jacobs-Kosmin, MD, FACP; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Complications of PAN include the following:

  • Cutaneous ulcerations
  • Extremity gangrene [34]
  • Organ infarction
  • Aneurysm rupture (intraorgan bleeding) - Aneurysmal ruptures have been reported to occur in the kidneys, liver, heart, pancreas, and axillary and brachial arteries. [35, 36, 37, 38, 39, 40]
  • Stroke
  • Encephalopathy
  • Myelopathy
  • Heart failure
  • Myocardial infarction/li>
  • Pericarditis
  • Renal failure
  • Gastrointestinal (GI) bleeding
  • Bowel infarction
  • Peripheral neuropathy

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