When is vertebral body bone biopsy performed in the workup of osteoporosis?

Updated: Aug 27, 2020
  • Author: Monique Bethel, MD; Chief Editor: Herbert S Diamond, MD  more...
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One may also perform a vertebral body bone biopsy when performing a therapeutic procedure such as kyphoplasty (see the images below) or vertebroplasty for fixation of a vertebral compression fracture.

In kyphoplasty, a KyphX inflatable bone tamp is pe In kyphoplasty, a KyphX inflatable bone tamp is percutaneously advanced into the collapsed vertebral body (A). It is then inflated, (B) elevating the depressed endplate, creating a central cavity, and compacting the remaining trabeculae to the periphery. Once the balloon tamp is deflated and withdrawn, the cavity (C) is filled under low pressure with a viscous preparation of methylmethacrylate (D).
Osteoporosis. Lateral radiograph demonstrates mult Osteoporosis. Lateral radiograph demonstrates multiple osteoporotic vertebral compression fractures. Kyphoplasty has been performed at one level.
Osteoporosis. Lateral radiograph of the patient se Osteoporosis. Lateral radiograph of the patient seen in the previous image following kyphoplasty performed at 3 additional levels.
Percutaneous vertebroplasty, transpedicular approa Percutaneous vertebroplasty, transpedicular approach.

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