What are the ISCD guidelines on the use of peripheral quantitative CT (pQCT) in the workup of osteoporosis?

Updated: Jan 20, 2021
  • Author: Rachel Elizabeth Whitaker Elam, MD, MSc; Chief Editor: Herbert S Diamond, MD  more...
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The following are the official positions of the ISCD on pQCT of the radius [5] :

  • pQCT of the forearm at the ultra-distal radius cannot be used for fracture risk assessment of the spine, but does predict hip fragility fractures in postmenopausal women

  • There is insufficient evidence to recommend pQCT for fracture risk prediction in men

  • As with QCT of the spine, pQCT of the radius cannot be used to diagnose osteoporosis based on the WHO diagnostic classification

  • As with QCT of the spine, pQCT of the radius along with clinical risk factors can be used to initiate pharmacologic treatment if central DXA cannot be obtained

  • pQCT measurements of the trabecular and total BMD of the ultra-distal radius can be used to monitor age-related BMD changes

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