What is the mnemonic for osteoporotic risk factors?

Updated: Jan 20, 2021
  • Author: Rachel Elizabeth Whitaker Elam, MD, MSc; Chief Editor: Herbert S Diamond, MD  more...
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A potentially useful mnemonic for osteoporotic risk factors is OSTEOPOROSIS, as follows:

  • L Ow calcium intake
  • Seizure meds (anticonvulsants)
  • Thin build
  • Ethanol intake
  • Hyp Ogonadism
  • Previous fracture
  • Thyr Oid excess
  • Race (white, Asian)
  • Other relatives with osteoporosis
  • Steroids
  • Inactivity
  • Smoking

Exposure to the antibacterial agent triclosan may increase the risk for osteoporosis in women. Analysis of data on 1848 women from the 2005-2010 US National Health and Nutrition Examination Survey (NHANES) showed that women in the highest tertile of urinary triclosan level had lower BMD in the total femur, intertrochanter, and lumbar spine; compared with women in the lowest tertile, those in the highest tertile were more likely to have increased prevalence of intertrochanter osteoporosis (odds ratio (OR)=2.464, 95% CI = 1.190, 5.105). [67]

In animal studies, triclosan has been found to disrupt hormone activity, and in vitro studies have shown that it can cause interstitial collagen accumulation and an increase in trabecular bone. The US Food & Drug Administration has banned triclosan from consumer hand sanitizers and other antiseptics, but it continues to be used in a variety of consumer products—including clothing, kitchenware, furniture, and toys—to prevent bacterial contamination. [67]

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