Which prenatal and postnatal factors increase the risk for osteoporosis in older adults?

Updated: Jan 20, 2021
  • Author: Rachel Elizabeth Whitaker Elam, MD, MSc; Chief Editor: Herbert S Diamond, MD  more...
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Prenatal and postnatal factors contribute to adult bone mass. In one study, the health of the mother in pregnancy, the infant’s birth weight, and the child’s weight at age 1 year were predictive of adult bone mass in the seventh decade for men and women. [50] It is postulated that growth in the first year of life programs growth hormone secretion, and that this programming is maintained into the seventh decade. [51] Higher birth weight and rapid growth in the first year of life predicted increased bone mass in adults aged 65-75 years. Maternal nutritional imbalance and deficiency may have an effect that is transmitted to the next generation. [52]

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