What are the American College of Rheumatology (ACR) guidelines for the treatment of glucocorticoid-induced osteoporosis?

Updated: Sep 26, 2019
  • Author: Monique Bethel, MD; Chief Editor: Herbert S Diamond, MD  more...
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Guidelines from the American College of Rheumatology for the treatment of glucocorticoid- induced osteoporosis include the following [12] :

  • Categorization of patients by fracture risk (using the FRAX score)

  • In appropriate patients, initiation of treatment with agents including alendronate, risedronate, zoledronic acid, and teriparatide (in those patients at highest risk)

Other approved agents include the following:

  • Romosozumab: For treatment of osteoporosis in postmenopausal women who are at high risk for fracture 
  • Denosumab: For treatment of glucocorticoid-induced osteoporosis 

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