Which medications in the drug class Antidepressants, SNRIs are used in the treatment of Osteoarthritis?

Updated: Oct 12, 2020
  • Author: Carlos J Lozada, MD; Chief Editor: Herbert S Diamond, MD  more...
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Antidepressants, SNRIs

The selective serotonin-norepinephrine reuptake inhibitor (SNRI) duloxetine may be effective for reducing osteoarthritis pain.

Duloxetine (Cymbalta)

Potent inhibitor of neuronal serotonin and norepinephrine reuptake. Indicated for chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain.

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