Which medications in the drug class Analgesic, Topical are used in the treatment of Osteoarthritis?

Updated: Oct 12, 2020
  • Author: Carlos J Lozada, MD; Chief Editor: Herbert S Diamond, MD  more...
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Analgesic, Topical

Topical analgesics are used for osteoarthritis involving relatively superficial joints, such as the knee joint and the joints of the hands. They are much less effective for deeper joints, such as the hip joint.

Capsaicin (Qutenza)

Capsaicin is a topical analgesic of choice in osteoarthritis. Derived from plants of the Solanaceae family, it may render skin and joints insensitive to pain by depleting substance P in peripheral sensory neurons. Capsaicin must be used for at least 2 weeks for the full effects to be appreciated.

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