Which medications are used in the treatment of osteoarthritis (OA)?

Updated: Oct 12, 2020
  • Author: Carlos J Lozada, MD; Chief Editor: Herbert S Diamond, MD  more...
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Pharmacologic agents used in the treatment of osteoarthritis include the following:

  • Acetaminophen
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), oral and topical (eg, diclofenac topical [159] )
  • Calcium channel blocker/COX-2 inhibitor combination
  • Intra-articular corticosteroids
  • Intra-articular sodium hyaluronate
  • Opioids
  • Duloxetine
  • Muscle relaxants
  • Nutraceuticals (eg, glucosamine/chondroitin sulfate)

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