How do NSAIDs affect blood pressure and kidney function when used for treatment of osteoarthritis (OA)?

Updated: Jun 10, 2020
  • Author: Carlos J Lozada, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

All NSAIDs had deleterious effects on blood pressure, edema, and kidney function. However, the AHRQ found no consistent clinically relevant differences between celecoxib, partially selective NSAIDs, and nonselective NSAIDs with regard to the risk of hypertension, heart failure, or impaired kidney function. [80]


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