What is the role of mesenchymal stem cell therapy in the treatment of osteoarthritis (OA)?

Updated: Jun 10, 2020
  • Author: Carlos J Lozada, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Mesenchymal stem cell therapy continues to be a promising investigational approach to knee osteoarthritis. [71, 72] However, the improvement reported with stem cell therapy has been modest, a placebo effect remains possible, and the quality of the supporting evidence has been questioned. [73, 74] In addition, the variability in mesenchymal stem cell injection, including timing, frequency, and culturing mode, warrant further research, as does the possible long-term risk.


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