Which genes have genome-wide association studies (GWAS) identified as having an etiologic role in osteoarthritis (OA)?

Updated: Oct 12, 2020
  • Author: Carlos J Lozada, MD; Chief Editor: Herbert S Diamond, MD  more...
  • Print

Genome-wide association studies (GWAS) have identified an association between osteoarthritis of large joints and the MCF2L gene. This gene is key in neurotrophin-mediated regulation of peripheral nervous system cell motility. [57]

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!