What is the role of genetics in the etiology of osteoarthritis (OA)?

Updated: Jun 10, 2020
  • Author: Carlos J Lozada, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

A hereditary component, particularly in osteoarthritis presentations involving multiple joints, has long been recognized. [48, 49, 50] Several genes have been directly associated with osteoarthritis, [51] and many more have been determined to be associated with contributing factors, such as excessive inflammation and obesity.


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