What are the Single Hub and Access point for pediatric Rheumatology in Europe (SHARE) treatment guidelines for lupus nephritis?

Updated: Mar 04, 2019
  • Author: Lawrence H Brent, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
  • Print
Answer

Recommendations for management based on the International Society of Nephrology/Renal Pathology Society 2003 classification system include the following [79] :

  • Class I: Treatment should be guided by symptoms
  • Class II: Low-dose prednisone, followed by a disease-modifying antirheumatic drug in patients who have 3 months of persistent proteinuria or develop prednisone dependency.
  • Class III/IV: Induction with mycophenolate mofetil (MMF) or intravenous cyclophosphamide plus steroids; maintenance treatment for at least 3 years with MMF, azathioprine, or both
  • Class V: MMF with low-dose prednisone for induction; maintenance treatment with MMF

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!