Which anti-CD20 monoclonal antibodies are used in the treatment of lupus nephritis?

Updated: Mar 04, 2019
  • Author: Lawrence H Brent, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Other anti-CD20 monoclonal antibodies have been used experimentally for lupus nephritis; for example, in patients who respond to rituximab but develop intolerable adverse effects. These include the following [66] :

  • Ocrelizumab (humanized)
  • Ofatumumab (human) [67]
  • TRU-015 (anti-CD20 small modular immunopharmaceutical [SMIP])

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