What is the principal goal of therapy in lupus nephritis?

Updated: Sep 22, 2020
  • Author: Lawrence H Brent, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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The principal goal of therapy in lupus nephritis is to normalize renal function or, at least, to prevent the progressive loss of renal function. Therapy differs depending on the pathologic lesion. [25, 42] It is important to treat extrarenal manifestations and other variables that may affect the kidneys. Patients should be on hydroxychloroquine if possible, as there are data to support that this improves outcomes in patients who have lupus nephritis, in addition to reducing lupus-related flares and disease damage accrual. [43]

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