What is the optimal biomarker panel in the assessment of active lupus nephritis in children?

Updated: Mar 04, 2019
  • Author: Lawrence H Brent, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

In an international study, Smith and colleagues reported that a panel of novel urinary biomarkers can accurately identify active lupus nephritis in children. [33] These authors concluded that the optimal biomarker panel would include the following:

  • Alpha-1-acid glycoprotein (AGP)
  • Ceruloplasmin
  • Lipocalin-like prostaglandin D synthase (LPGDS)
  • Transferrin (area under the curve [AUC] 0.920)

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