Which lab tests are used to evaluate renal function in systemic lupus erythematosus (SLE) with suspected lupus nephritis?

Updated: Mar 04, 2019
  • Author: Lawrence H Brent, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Laboratory tests to evaluate renal function in SLE patients include the following:

  • Blood urea nitrogen (BUN) testing

  • Serum creatinine assessment

  • Urinalysis (to check for protein, red blood cells [RBCs], and cellular casts)

  • A spot urine test for creatinine and protein concentration (normal creatinine excretion is 1000 mg/24 h/1.75 m2; normal protein excretion is 150-200 mg/24 h/1.75 m2; normal urinary protein-to-creatinine ratio is <0.2)

  • A 24-hour urine test for creatinine clearance and protein excretion


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