Which factors affect the development of histologic type of lupus nephritis?

Updated: Feb 08, 2021
  • Author: Lawrence H Brent, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
  • Print

The histologic type of lupus nephritis that develops depends on numerous factors, including the antigen specificity and other properties of the autoantibodies and the type of inflammatory response that is determined by other host factors. In more severe forms of lupus nephritis, proliferation of endothelial, mesangial, and epithelial cells and the production of matrix proteins lead to fibrosis. [4]

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!