Which lab tests are performed in the evaluation of lupus nephritis?

Updated: Mar 04, 2019
  • Author: Lawrence H Brent, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Laboratory tests to evaluate renal function in SLE patients include the following:

  • Blood urea nitrogen (BUN) testing

  • Serum creatinine assessment

  • Urinalysis (to check for protein, red blood cells [RBCs], and cellular casts)

  • Spot urine test for creatinine and protein concentration

  • 24-hour urine test for creatinine clearance and protein excretion

Laboratory tests for SLE disease activity include the following:

  • Antibodies to double-stranded DNA (dsDNA)

  • Complement (C3, C4, and CH50)

  • Erythrocyte sedimentation rate (ESR)

  • C-reactive protein (CRP)


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